CDC - NIOSH Pocket Guide to Chemical Hazards - Phthalic anhydride Carboxylic acids donate hydrogen ions if a base is present to accept them. Effects of long-term or repeated exposure. © ILO and WHO 2017. Commission Regulation (EU) No 2015/830 of 28 May 2015. Formula: C 8 H 4 O 3 / C 6 H 4 (CO) 2 O Molecular mass: 148.1 It is an isomer of isophthalic acid and terephthalic acid. The solution in water is a weak acid. The toxicological properties of SECTION 1: Identification of the substance/mixture and of the company/undertaking 1.1. Reacts with strong oxidants, strong acids, strong bases and reducing agents. May cause gastrointestinal irritation with nausea, vomiting and PubChem Substance ID 24859242. View information & documentation regarding Phthalic acid, including CAS, MSDS & more. cause respiratory tract irritation. Phthalic acid Hazards. Acids accelerate the reaction with water. 1.3 Details of the supplier of the safety data sheet Company : Central Drug House (P) Ltd 7/28 Vardaan House New Delhi-10002 INDIA Additionally, the classification provided by companies to ECHA in CLP notifications identifies that this substance causes serious eye irritation, is harmful if swallowed, causes skin irritation and may cause respiratory irritation. Although phthalic acid is of modest commercial importance, the closely related derivative phthalic anhydride is a commodity chemical produced on a large scale. This generates explosion hazard. Possible risk of irreversible effects. Thus, water is a very good recrystallization solvent for phthalic acid. diarrhea. Empirical Formula (Hill Notation) C 8 H 4 O 3. 2-dicarboxylic acid", "o-phthalic acid", "o-phthalic acid" Section 2 - HAZARDS IDENTIFICATION CANADIAN WHMIS SYMBOLS EMERGENCY OVERVIEW RISK May cause SENSITIZATION by skin contact. It is a conjugate acid of a phthalate (1-) and a phthalate . Sigma-Aldrich offers a number of Phthalic acid products. this substance have not been fully investigated. Phthalic acid is one of three isomers of benzenedicarboxylic acid, the others being isophthalic acid and terephthalic acid. May Phthalic Anhydride Life Cycle Diagram..... 36 Figure 2-12. 3-Nitrophthalic acid, 95%. Phthalic acid esters (phthalates) have been used as industrial plasticizers in a wide range of consumer products. Phthalic acid is an aromatic dicarboxylic acid, with formula C 6 H 4 (CO 2 H) 2. Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Phthalic acid is very soluble in boiling water, 18 g/100 mL, and is much less soluble in chilled (14°C) water, 0.54 g/100 mL. Although phthalic acid is of modest commercial importance, the closely related derivative phthalic anhydride is a commodity chemical produced on a … As part It is an isomer of isophthalic acid and terephthalic acid. Outline the steps of the following procedure. Molecular Weight 148.12 . Finely dispersed particles form explosive mixtures in air. EINECS 210-030-8. m-Nitrophthalic acid. May cause eye irritation. Studies show that exposure to phthalic anhydride can cause rhinitis, chronic bronchitis, and asthma. ISOPHTHALIC ACID is a carboxylic acid. Phthalic anhydride ACS reagent, ≥99% CAS Number 85-44-9. Not listed EC No. This can happen as a direct influence on the synthesis of male hormones called androgens. The reactions are sometimes slow, but can become violent when local heating accelerates their rate. Caution! Ingestion: Phthalic acid is a benzenedicarboxylic acid cosisting of two carboxy groups at ortho positions. 210-211 °C (Decomposes) SynQuest 205 °C (Decomposes) Alfa Aesar 210 °C Jean-Claude Bradley Open Melting Point Dataset 14144: 230 °C Jean-Claude Bradley Open Melting Point Dataset 16989, 28454: 205 °C (Decomposes) Alfa Aesar 41770, A14450 210-211 °C (Decomposes) SynQuest 52322, 210-211 °C (Decomposes, Literature) LabNetwork LN00194231 204-209 °C LabNetwork LN00194231 The substance is irritating to the eyes, skin and respiratory tract. CRYSTALLINE POWDER. The maximum sorption capacity of the resin predicted by the Langmuir model were 397.8 mg g−1 for the phthalic acid and 331.3 mg g−1 for isophthalic acid. Physical dangers If appropriate, moisten first to prevent dusting. properties of this material have not been fully investigated. 3-nitrophthaiic acid. May cause respiratory tract irritation. Beilstein/REAXYS Number 118515 . Phthalic acid (PA) is chemical substance that is an aromatic dicarboxylic acid, with the chemical formula C 6 H 4 (COOH) 2.It is used primarily to make corrosion inhibitors that are applied to metal substrate surfaces. 3-nitrophtalic acid. 3-nitrobenzene-1,2-dicarboxylic acid. MFCD00007138. Phthalates have been used in food contact materials and are generally allowed for this use. with the financial assistance of the European Commission. 3-Nitrophthalicacid. Molecular mass: 166.1 Dust explosion possible if in powder or granular form, mixed with air. Chronic: Chemical Name : PHTHALIC ANHYDRIDE CAS Number : 85-44-9 EC Number : 201-607-5 Molecular Formula : C8H4O3 Molecular Weight : 148.1 Synonyms : Phthalic Acid Anhydride, 1,3-Isobenxofurandione, 1,2 Benzene Carboxylic Acid Anhydride It is narcotic in high concentrations. It is an isomer of isophthalic acid and terephthalic acid. ACUTE/CHRONIC HAZARDS: This compound is an irritant of the skin, eyes, mucous membranes, and respiratory tract. 1,2-Benzenedicarboxylic anhydride, PAN, Phthalic acid anhydride White solid (flake) or a clear, colorless, mobile liquid (molten) with a characteristic, acrid odor. Breakdown of all 141 C&L notifications submitted to ECHA Avoid dust formation and control ignition sources. No information found. Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Attacks many metals in the presence of water. In high concentrations, it can cause narcosis. Phthalic acid is an aromatic dicarboxylic acid, with formula C6H4(CO2H)2. NO open flames. Incompatible materials: Strong acids, strong bases, strong oxidizing agents, strong reducing agents. Studies have shown that when administered to men Phthalic influences the process of formation of spermatozoa said process spermatogenesis. Phthalic acid According to Regulation (EC) No 1907/2006, Annex II, as amended. Thermal decomposition can lead to release of irritating gases and vapors. Phthalic acid is an aromatic dicarboxylic acid, with formula C6H4(CO2H)2. nitrophthalic acid. It is an isomer of isophthalic acid and terephthalic acid. Closed system, dust explosion-proof electrical equipment and lighting. Although phthalic acid is of modest commercial importance, the closely related derivative phthalic anhydride is a commodity chemical produced on a large scale. They react in this way with all bases, both organic (for example, the amines) and inorganic. Appearance: white crystals. Inhalation: Inhalation of vapor, fume or dust is a primary irritant. Eye: Product name : Phthalic Acid CAS-No. Phthalic acid and isophthalic acid loading isotherm studies have been performed and experimental data were analyzed by Freundlich, Langmuir and Dubinin–Radusckevich (D-R) equations. NSC 3120. Combustible. Target Organs: No data found. 1,2-benzenedicarboxylic acid.....81 A.1.2.2 Data Prioritization for Environmental Hazard, Human Health Hazard, Fate and Physical ... Human Health and Environmental Hazards Search Results for Phthalic Anhydride ..... 25 Figure 2-11. Irritating to eyes, respiratory system and skin. PHTHALIC ANHYDRIDE reacts exothermically with water. The toxicological Phthalic acid is an aromatic dicarboxylic acid, with formula C6H4(CO2H)2. Prevent deposition of dust. Incompatible with acids, strong oxidizing agents, alcohols, amines, and bases. been fully investigated. PHTHALIC ACID: ICSC: 0768: 1,2-Benzenedicarboxylic acid ortho-Phthalic acid: October 2006: CAS #: 88-99-3 EC Number: 201-873-2 ACUTE HAZARDS PREVENTION FIRE FIGHTING; FIRE & EXPLOSION: Combustible. Hazards Identification. Wash away remainder with plenty of water. NO open flames. cause respiratory and digestive tract irritation. MDL number MFCD00005918. phthalic acid - self classification Implementation: EU Remarks: self classification according to Directive 67/548/EEC Related composition Related composition: Composition 2 Classification open all close all. May cause skin irritation. This produces phthalic acid. Reacts violently with copper oxide and sodium nitrite on heating. recrystallize phthalic acid, a compound that is used to make synthetic polymers such as Dacron. Phthalic acid is an aromatic dicarboxylic acid, with formula C6H4(CO2H)2. Rinse with plenty of water for several minutes (remove contact lenses if easily possible). If heated, dust or fume may OSHA Vacated PELs: Phthalic acid, monopotassium salt: No OSHA Vacated PELs are listed for this chemical. A nuisance-causing concentration of airborne particles can be reached quickly when dispersed, especially if powdered. Formula: C8H6O4 / C6H4(COOH)2 Sweep spilled substance into covered containers. Physical State; Appearance Chemical dangers Specific Hazards Arising from the Chemical Fine dust dispersed in air may ignite. Please contact Fisher Scientific for shipping information. Decomposes on contact with hot water. Closed system, dust explosion-proof electrical equipment and lighting. POTENTIAL HEALTH EFFECTS Phthalic anhydride reaction on human health is generally an asthma-rhinitis-conjunctivitis syndrome or a delayed reaction and influenza-like symptoms and with increased immunoglobulin (immunoglobulin E, immunoglobulin G) levels in the blood. Skin: A recent food safety concern has arisen from the unapproved use of certain phthalates in a broad range of food/nutraceutical ingredients from Taiwan [53]. Health Hazard. Potential Health Effects Prepared by an international group of experts on behalf of ILO and WHO, NSC3120. Inhalation: Use water spray, powder, alcohol-resistant foam, carbon dioxide. Phthalic acid esters are documented to accumulate irreversibly in organisms, of which DBP has been reported to exhibit not only carcinogenesis in diverse aquatic animals and hydrophytes but also adverse effects on male reproductive systems, leading to threats to the freshwater ecosystem. Phthalic acid, also called 1, 2-benzenedicarboxylic Acid, colourless, crystalline organic compound ordinarily produced and sold in the form of its anhydride. phthalic acid, copper salt Score: #495 in Physics , #1252 in Biology , #1446 in Chemistry 1,2-Benzenedicarboxylic acid, 3-nitro-3-nitro phthalic acid. Their reactions with bases, called "neutralizations", are accompanied by the evolution of substantial amounts of heat. Finely dispersed particles form explosive mixtures in air. Physical hazards. Coughing, choking, as well as headache and dizziness can occur. It has a role as a human xenobiotic metabolite. Although phthalic acid is of modest commercial importance, the closely related derivative phthalic anhydride is a commodity chemical produced on a large scale. Decomposes at 191°CRelative density (water = 1): 1.6 Solubility in water, g/100ml at 25°C: 0.625 (poor)Relative vapour density (air = 1): 5.7 Flash point: 168°C c.c.Octanol/water partition coefficient as log Pow: 0.73. Phthalic acid, 3-nitro-3-nitro-phthalic acid. Phthalic Acid Section 1: Identification of the substance/mixture and of the company / undertaking 1.1 Product Identifier Product Name Phthalic Acid Other Names Benzene-1,2-Dicarboxylic Acid CAS No. ... Reacts with moisture to give phthalic acid, which can corrode metals liberating hydrogen. In primate Phthalic orally observed change in the levels of sex hormones. Rinse and then wash skin with water and soap. Inhalation risk : 88-99-3 1.2 Relevant identified uses of the substance or mixture and uses advised against Identified uses : Laboratorychemicals, Industrial & for professional use only. It is an isomer of isophthalic acid and terephthalic acid. 201-873-2 Product Code S0001842 1.2 Relevant identified uses of the substances or mixture and uses advised against May cause eye and skin irritation. Effects of short-term exposure NACRES NA.21 SYMPTOMS: Symptoms of exposure to this compound may include irritation of the skin, eyes, mucous membranes, and respiratory passages. 88-99-3 Index No. Although phthalic acid is of modest commercial importance, the closely related derivative phthalic anhydride is a commodity chemical produced on a large scale. The toxicological properties of this substance have not EC Number 201-607-5. Food contact materials and are generally allowed for this use a benzenedicarboxylic acid, with the assistance! 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