Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. c. Unstable plaques can release their lipid content into the blood stream. Cardiac CT and MRI are the best imaging tools for diagnosing cardiac lipomas as they identify fat with high specificity. Fat necrosis and lipoma If fatty tissue in the breast becomes damaged or broken down, fat necrosis may occur. Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. Now customize the name of a clipboard to store your clips. Overweight or obesity - overweight is having extra body weight from muscle, bone, fat, and/or water - obesity is having a high amount of extra body fat. Looks like you’ve clipped this slide to already. Thrombus • Most common intra-cardiac mass • Location often associated with cardiac pathology –LV thrombus •Acute MI –Estimated 4-15% patients with anterior MI (LV apex) •Dilated cardiomyopathy –DDx: false tendons, trabeculations, artifacts, apical hypertrophy, tumors, non-compaction, Loeffler’s –LA thrombus •Appendage •Body PRESENTED BY PHARM. Rim of Arterial vs. venous thrombosis. Atherosclerosis is the most common arterial Fibroblasts eventually invade the thrombus, scarring vein wall and destroying valves. via MI\), it can be hard to tell pre-mortem from post-mortem clots. MRI has similar reported sensitivity and specificity for detecting thrombus in the renal vein of 86–94% and 75–100%, respectively, as well as 100% accuracy for detecting IVC thrombus [ 79 , 80 ]. Check the full list of possible causes and conditions now! 2004 Feb. 56(2):356-62. . Fat.— The presence of fat is easily recognized owing to its high attenuation at CT or its high signal intensity at T1-weighted MR imaging with loss of signal intensity on fat-suppressed images. MAMZA JOSHUA 3rd, OCT., 2014 2. Large vessel thrombotic strokes typi… See our Privacy Policy and User Agreement for details. In addition, the authors' laboratory studied nearly 100 cases of sudden coronary death and found that 60% of all thrombi could be attributed to plaque rupture and 40% to erosions. CAD is asymptomatic in most of the population. INTRODUCTION Problems of the vascular system includes disorders of the arteries and veins. Patency may be restored valve damage is permanent, affecting directional flow. 24. Atherosclerosis, chronic disease caused by the deposition of fats, cholesterol, calcium, and other substances in the innermost layer of endothelium of the large and medium-sized arteries. Scalp Fat ~ -84.5 HU Air ~ -966.3 HU Tissue Density Differences Lower density substances allow more photons pass through to the detectors, resulting in a grayer or blacker appearance on … Most commonly, PE is due to a blood clot or thrombus. MRI has similar reported sensitivity and specificity for detecting thrombus in the renal vein of 86–94% and 75–100%, respectively, as well as 100% accuracy for detecting IVC thrombus [79, 80]. Dietary cholesterol esters are de-esterified into free cholesterol by these same mechanisms. When formed in the heart or aorta, thrombi may have grossly (and microscopically) apparent laminations, called Wong MW, Tsui HF, Yung SH, Chan KM, Cheng JC. Fat-soluble vitamins. Increased Jugular Venous Pressure & Mural Thrombus Symptom Checker: Possible causes include Acute Myocardial Infarction. Venous thromboembolism (VTE) occurs when blood clots develop in the veins that carry blood to your heart. A vena cava filter may be used in some people who cannot take blood thinners. At the proximal and distal ends near the site of white thrombosis there is another type of thrombus composed of layers of red blood cells and fibrin and is therefore called red thrombus. Severity assessment . The thrombus propagates in the direction of the blood flow. Fat emboli are common and typically resolve on their own, but rarely they can lead to fat embolism syndrome (FES), a serious condition that can result in respiratory failure. Normally vessels don't stand out in lung sections. A thrombotic stroke is a type of ischemic stroke that occurs when a blood clot, also called a thrombus, forms and blocks blood flow through the artery in which it formed. FAT EMBOLISM SYNDROME & PULMONARY EMBOLISM FARAH AZUREEN ABD ZAIM 2. It includes deep vein thrombosis and pulmonary thrombosis. Small pulmonary emboli . Vessels with emboli are DISTENDED with a "pinkish-hyaline appearance" of clot instead of RBC filled lumen. Final thrombus burden 1. Color Doppler sonography has reported sensitivities and specificities for detecting thrombus in the renal veins of 75% and 96%, respectively, with 100% accuracy for detection of thrombus in the IVC . These include increased hepatic synthesis of fatty acids (alcohol), decreased hepatic oxidation or utilization of fatty acids (carbon tetrachloride, high-dose tetracycline), impaired release of hepatic lipoproteins, and excessive mobilization of fatty acids from adipose tissue (starvation, steroids, alcohol). See our User Agreement and Privacy Policy. VENOUS THROMBOEMBOLISM Compositeterm for DVT &PE The presence of thrombus with in deep veinsis termed as deep vein thrombosis It is a life threatening condit… PE can be classified according to : The presence or absence of hemodynamic stability (hemodynamically Thrombus formation after plaque disruption can lead to acute coronary syndrome 1,2. Atherosclerosis, chronic disease caused by the deposition of fats, cholesterol, calcium, and other substances in the innermost layer of endothelium of the large and medium-sized arteries. Continuous pulse oximeter monitoring for inapparent hypoxemia after long bone fractures. Blokhuis TJ, Pape HC, Frölke JP. Pharmacologyonline 3: 420-442 (2009) Newsletter Jagdish Kakadiya — A primary pulmonary artery sarcoma is an uncommon cause of an intraluminal arterial filling defect. An unstable plaque has thinner walls, which can easily rupture and trigger thrombosis, which can completely occlude the artery. Tumor thrombus from invasion of the portal vein by hepatoma is confirmed by spectral Doppler demonstration of arterial waveforms in the thrombus within the portal vein. Arteries are blood vessels that carry blood from the heart to the rest of the body and the heart muscle. Catheter-assisted thrombus removal uses a flexible tube to reach a blood clot in your lung. A thrombus is made up of fibrin, platelets and red blood cell and few inflammatory cells. The embolisms can have their causes in other types of materials, not only in blood clots , for example in fat globules, bubbles of air or gas and any other type of foreign body that enters the blood circulation. MANAGEMENT OF THROMBUS BURDEN DURING PAMI. One of the most common recognized scenarios is called coronary thrombosis of a coronary artery, causing myocardial infarction (a heart attack). 1977 Aug. 17(8):621-9. . In this presentation we tried to discuss about thrombosis,how it occurs,causes of thrombosis,classification of thrombosis,It's natural history, how to prevent thrombosis & what to do if thrombosis already occurred. Clipping is a handy way to collect important slides you want to go back to later. Talk to our Chatbot to narrow down your search. Fat-soluble vitamins. NORMAL HEMOSTASIS The general sequence of events in hemostasis at the site of vascular injury is shown in Figure 4-6 . Large vessel stroke occurs in the larger blood-supplying arteries of the brain, such as the carotid artery or middle cerebral artery. MRI, with its multiplanar capability, is probably the best technique for identifying the superior extent of IVC involvement [ 49 , 81 ]. The fat-only images offer the potential for fat-quantification. Atherosclerosis is the most common arterial abnormality characterized as arteriosclerosis, which is … Primary Pulmonary Artery Sarcoma. We use your LinkedIn profile and activity data to personalize ads and to show you more relevant ads. The temporal pattern of presentation (acute, subacute, or chronic). FAT EMBOLISM SYNDROME BACKGROUND EPIDEMIOLOGY CAUSES PATHOPHYSIOLOGY CLINICAL FEATURES DIAGNOSTIC CRITERIA … Fat Necrosis of the Breast Symptom Checker: Possible causes include Benign Neoplasm of the Breast. When severe enough it can cause angina or an acute coronary syndrome including myocardial infarction. Thromb Haemost. [2][3] • After initial injury, there is a brief period of arteriolar vasoconstriction, largely attributable to reflex neurogenic mechanisms and augmented by the local secretion of factors such as endothelin (a potent endothelium-derived vasoconstrictor). The thrombus formed at the rupture site is called white thrombus due to its grossly white appearance of rich platelet. renal artery occlusion is considered a grade V renal injury; iatrogenic (e.g. If you continue browsing the site, you agree to the use of cookies on this website. Antemortem thrombus Postmortem clot Adherent to wall Not adherent to vessel wall Red in colour Fibrin with red cells and leucocytes in a haphazard network (gelatinous) Upper layer resembling chicken fat Lines of zahn present No lines of zahn – bland and non – … A minor disadvantage is an increase in minimum TR value (required to allow time for collection of the multiple echoes). A thrombotic stroke may also be called a cerebral thrombosis, a cerebral infarction or a cerebral infarct. Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. causing the formation of a thrombus that will rapidly slow or stop blood flow, leading to death of the tissues fed by the artery in approximately 5 minutes. a. 2. thrombosis, embolism, infarction dr. sinhasan- mdzah, No public clipboards found for this slide. Peripheral arterial disease is a term used to describe a wide variety of conditions affecting arteries in the neck, abdomen and extremities. If you continue browsing the site, you agree to the use of cookies on this website. 90% of individuals with severe skeletal injuries, though <10% have any clinical findings. Triglycerides (TGs) and cholesterol contribute most to disease, although all lipids are physiologically important. If you continue browsing the site, you agree to the use of cookies on this website. Check the full list of possible causes and conditions now! 1990 Jan. 18(1):42-6. . 6 hemodynamic disorders 1. Background: The prognostic significance of venous tumor thrombus extension in patients with renal cell carcinoma (RCC) is a matter of many controversies in the current literature. thrombus. J 2- composed of platelets and fibrin. We examined the feasibility and safety of lesion formation using high-amplitude, bipolar pulsed electric fields delivered from a … Natural History If thrombus forms inside blood vessel, then possible outcomes: Embolisation Lysis Ischaemia Organisation 8. 1. a thrombus (or thrombi) that originates somewhere in the venous system or in the right side of the heart. See our User Agreement and Privacy Policy. BALAKUMARAN. Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. An unstable plaque has thinner walls, which can easily rupture and trigger thrombosis, which … Morphology of thrombus (cont.) Clipping is a handy way to collect important slides you want to go back to later. may occur. You can change your ad preferences anytime. • Normal fluid homeostasis is maintained by vessel wall integrity, intravascular pressure and osmolarity within certain physiologic ranges.• Changes in intravascular volume, pressure, or protein content, or alterations in end CAD may also present with heart failureor sudden cardiac death. In patients with RCC and VTT, the presence of a friable thrombus is an independent predictor of CSS. Fat emboli are common and typically resolve on their own, but rarely they can lead to fat embolism syndrome (FES), a serious condition that can result in respiratory failure. Normal Haemostasis Process of maintaining blood in a fluid, clot – free state in normal vasculature and rapidly forming a localized haemostatic plug at the site of vascular injury The pathologic opposite of haemostasis is thrombosis The fat-only images offer the potential for fat-quantification. a. Filling defect in superior mesenteric vein (arrow) represents thrombus. Wall of affected bowel is thickened with low- density center representing submucosal edema. THROMBUS BLOOD CLOT 1- Involves wall of blood vessels, formed elements of blood & blood clotting system. Embolism, obstruction of the flow of blood by an embolus, a particle or aggregate of substance that is abnormally present in the bloodstream. fibromuscular dysplasia (FMD) renal trauma. Eric Wong and Sultan Chaudhry Faculty reviewer: Dr. Peter L. Gross, Associate Professor, Division of Hematology and Thromboembolism, Department of Medicine (McMaster University) Definition Deep vein thrombosis (DVT) and pulmonary embolism (PE) are manifestations of the same pathological entity, called venous thromboembolism (VTE). We use your LinkedIn profile and activity data to personalize ads and to show you more relevant ads. This catastrophic event is called an infarction. Red blood cell and few inflammatory cells triggered, causing tenderness, swelling and. 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