Suručić R, Tubić B, Stojiljković MP, Djuric DM, Travar M, Grabež M, Šavikin K, Škrbić R. Mol Cell Biochem. -. See this image and copyright information in PMC. Epub 2013 May 24. Hence, the purpose of the study was to evaluate the effect of gallic acid and ellagic acid on intestinal transport and bioavailability of linagliptin, a p-gp substrate in diabetic rats. -, Shukla M, Gupta K, Rasheed Z, Khan KA, Haqqi TM. 2020 Nov 16:1-15. doi: 10.1007/s11010-020-03981-7. Units. National Center for Biotechnology Information, Unable to load your collection due to an error, Unable to load your delegates due to an error, HPLC chromatogram of ethyl acetate fraction showing the presence of punicalagin A&B collected at 14.1 min, HPLC chromatogram of ethyl acetate fraction showing the presence of ellagic acid collected at 22.6 min, Mass spectrum showing the presence of punicalagin A&B [M-H] -, Mass spectrum showing the presence of ellagic acid [M-H] -, Cell viability was determined from the 24 h culture of cells stimulated with LPS (1 μg/mL) in the presence of ellagic acid, gallic acid and punicalagin The data represent mean ± SD of, Effect of ellagic acid, gallic acid and punicalagin on nitrite production in LPS-stimulated RAW264.7 cells.  |  Gallic acid is easily freed from gallotannins by acidic or alkaline hydrolysis. Methods: 2005 Dec;28(12):1328-32. doi: 10.1007/BF02977896. The 4- O -glucoside was unambiguously identified by LC-MS in comparison with authentic reference material ( … Therefore, the antileishmania, cytotoxic, and immunomodulatory activities of GA and EA were evaluated in this study. Chemically it is 2,3,7,8-tetrahydroxy[1]benzopyranol[5,4,3-cde]benzopyran-5,10-dione ( Masamune et al., 2005 ) ( Fig. 2010 Jul 19;9:208. doi: 10.1186/1475-2875-9-208. Gallic acid (GA) and ellagic acid (EA) are two hydrolysates of corilagin, both of which possess strong antioxidant and anticancer effects [7–10]. -. Herbal Decoction Divya-Peedantak-Kwath Alleviates Allodynia and Hyperalgesia in Mice Model of Chemotherapy-Induced Peripheral Neuropathy via Modulation in Cytokine Response. Punica granatum (pomegranate), an edible fruit originating in the Middle East, has been used as a traditional medicine for treatment of pain and inflammatory conditions such as peptic ulcer. Overview Information Ellagic acid is a naturally occurring substance. Recent developments in antiinflammatory natural products. Bioavailable constituents/metabolites of pomegranate (Punica granatum L) prefentially inhibit COX-2activity exvivo and IL-I beta induced PGE2 production in human chondrocytes in vitro. Biomolecules. 2013 May;33(5):341-8. doi: 10.1016/j.nutres.2013.03.003. [2], Urolithins are microflora human metabolites of dietary ellagic acid derivatives. 2009;29(5):767–820. Please enable it to take advantage of the complete set of features! Int J Interferon Cytokine Mediator Res. A … The best sources of ellagic acid in the diet are strawberries, raspberries, blackberries, cherries, and walnuts. Seeram NP, Adams LS, Henning SM, Niu Y, Zhang Y, Nair MG, Heber D. J Nutr Biochem. In young leaves of both plants, the incorporation rate of labeled … Preparation, characterization and therapeutic properties of gum arabic-stabilized gallic acid nanoparticles. The compounds are d-catechin, I-epicatechin, I-epigallocatechin, gallic acid, protocatechuic acid, and ellagic acid, in addition, gallocatechin in apples. Nevertheless, all tested PoPEx ligands showed significant binding affinity at the ACE2 predicted active site with all ligand-protein complexes stabilized through hydrogen bonds. [17], 2,3,7,8-Tetrahydroxy-chromeno[5,4,3-cde]chromene-5,10-dione, InChI=1S/C14H6O8/c15-5-1-3-7-8-4(14(20)22-11(7)9(5)17)2-6(16)10(18)12(8)21-13(3)19/h1-2,15-18H, InChI=1/C14H6O8/c15-5-1-3-7-8-4(14(20)22-11(7)9(5)17)2-6(16)10(18)12(8)21-13(3)19/h1-2,15-18H, Except where otherwise noted, data are given for materials in their, "The Formation of Ellagic Acid from Galloyl-Glycine by, "Protein glycation inhibitors from the fruiting body of, "Postharvest sensory and phenolic characterization of 'Elegant Lady' and 'Carson' peaches", "187 Fake Cancer 'Cures' Consumers Should Avoid", "Warning Letter sent to Millennium Health", "Warning Letter sent to Kenton Campbell at Prime Health Direct, Ltd", "Gastrointestinal microflora, food components and colon cancer prevention", Allopregnanedione (5α-dihydroprogesterone), https://en.wikipedia.org/w/index.php?title=Ellagic_acid&oldid=957891010, Pages using collapsible list with both background and text-align in titlestyle, Articles containing unverified chemical infoboxes, Srpskohrvatski / српскохрватски, Creative Commons Attribution-ShareAlike License, This page was last edited on 21 May 2020, at 00:29. doi: 10.1002/med.20156. Phyllanthus emblica L. (Euphorbiaceae) is a famous medicinal plant distributed in Asia countries especially in China. Results: Ellagic acid, gallic acid and punicalagin A&B potentially inhibited LPS-induced NO, PGE-2 and IL-6 production. Ellagic acid is a potent inhibitor with Kis of 13.4 and 7.5 μM, in contrast to gallic acid which displays Kis of 1.7 and 3.9 mM for GPb and GPa, respectively. Ellagic acid, gallic acid and punicalagin A&B potentially inhibited LPS-induced NO, PGE-2 and IL-6 production. Some foods contain a more complex version called ellagitannin. Ellagic acid is the dilactone of hexahydroxydiphenic acid. 2010;2(6):266–270. The striking feature of this study is the high amounts of all phenolic compounds in Armagnac, which had by far the highest concentrations of gallic acid, syringic acid, vanillin, and ellagic acid, as well as the second highest of vanillic acid, syringaldehyde, coniferaldehyde, and trimethoxyphenylacetic acid. doi: 10.3109/13880209.2011.611142. Nonsteroidal anti-inflammatory drugs: prostaglandins, indications, and side effects. 2012;50(4):429–438. [13] A number of U.S.-based sellers of dietary supplements have received Warning Letters from the Food and Drug Administration for promoting ellagic acid with claims that violate the Federal Food, Drug, and Cosmetic Act. The data represent the mean ± SD of, Effect of ellagic acid, gallic acid and punicalagin on PGE-2 production in LPS-stimulated RAW264.7 cells. Gallic acid and ellagic acid have been reported to inhibit p-glycoprotein (p-gp) and enhance the bioavailability of p-gp substrate drugs. Get the latest public health information from CDC: https://www.coronavirus.gov, Get the latest research information from NIH: https://www.nih.gov/coronavirus, Find NCBI SARS-CoV-2 literature, sequence, and clinical content: https://www.ncbi.nlm.nih.gov/sars-cov-2/. Zero-value entries. 2005 Jun;16(6):360-7. doi: 10.1016/j.jnutbio.2005.01.006. NIH The results indicate that ellagic acid, gallic acid and punicalagin may be the compounds responsible for the anti-inflammatory potential of P. granatum. [12], Ellagic acid has been marketed as a dietary supplement with a range of claimed benefits against cancer, heart disease, and other medical problems. The method employed in current study resulted in good peak shape of Gallic acid. Would you like email updates of new search results? HHS 2013 Nov;64(7):907-13. doi: 10.3109/09637486.2013.798268. Ardah MT, Bharathan G, Kitada T, Haque ME. 2011;3:19–27. hide show. Their food sources vary greatly, but in in general, phenolic acids are highly concentrated in the seeds and skins of … Gallic acid (GA) and ellagic acid (EA) are plant-derived phenolic compounds which are able to induce antiinflammatory, gastroprotective, and anticarcinogenic activities. Conclusion: What foods contain beneficial polyphenols and ellagic acid? Fijałkowska A, Muszyńska B, Sułkowska-Ziaja K, Kała K, Pawlik A, Stefaniuk D, Matuszewska A, Piska K, Pękala E, Kaczmarczyk P, Piętka J, Jaszek M. Sci Rep. 2020 Nov 18;10(1):20081. doi: 10.1038/s41598-020-76899-1. It plays an important role in food science as a dietary polyphenol consisting of a dimer of lactonized gallic acid. The cells were stimulated with 1 μg/ml of LPS only or with LPS plus various concentrations (50, 100, 150, 200 μg/mL) of for ellagic acid, gallic acid and punicalagin 6 h. IL-6 produced and released into the culture medium was assayed by ELISA method. Fruit is a food group that commonly contains both. The pharmacological use of ellagic acid-rich pomegranate fruit. Gallic acid and ellagic acid showed a good linear relationship between 7.375 and 236 μg/mL with a correlation coefficient of 0.9999, and between 3.625 and 116 μg/mL with a correlation coefficient of 0.9999 respectively. Keywords: It is widely biosynthesized in plants as a secondary metabolite. Short Description: Item Specification CAS No 5995-86-8 Molecular Formula C7H6O5 Appearance White crystalline powder Assay 99.0% min. The inhibitory effect of ellagic acid, gallic acid and punicalagin A&B were evaluated on the production of LPS-induced NO by Griess reagent, PGE-2 and IL-6 by immunoassay kit and prostaglandin E2 competitive ELISA kit, and COX-2 by Western blotting. *Please select more than one item to compare Balkrishna A, Sakat SS, Karumuri S, Singh H, Tomer M, Kumar A, Sharma N, Nain P, Haldar S, Varshney A. Epub 2013 Apr 15. The accuracy of the method was checked by a recovery study conducted at two different levels and the average percentage recovery was found to be 101.02% for gallic acid and 102.42% for ellagic acid. [16] Claims that ellagic acid can treat or prevent cancer in humans have not been proven. Med Res Rev. 2020 Oct 30;11:566490. doi: 10.3389/fphar.2020.566490. A wide range of constituents of T. arjuna were characterized and broadly grouped as 27 gallic acid and 52 ellagic acid derivatives.  |  This is the first report for the quantification of gallic acid and ellagic acid … Ellagic acid is a natural phenol antioxidant found in numerous fruits and vegetables. eCollection 2020. [9], The highest levels of ellagic acid are found in raw chestnuts, walnuts, pecans, cranberries, raspberries, strawberries, and grapes, as well as distilled beverages. There are many high ellagic acid foods you can add to your diet starting today. There was little decarboxylation of gallic acid in NSSC pulping liquors. Search results for gallic acid* at Sigma-Aldrich. However, only ellagic acid functions with glucose in a strongly synergistic mode. Arch Pharm Res. Both compounds are competitive inhibitors with respect to the substrate, glucose-1-phoshate, and non-competitive to the allosteric activator, AMP. When heated with concentrated sulfuric acid, gallic acid converts to rufigallol. [14][15], Urolithins, such as urolithin A, are microflora human metabolites of dietary ellagic acid derivatives that are under study as anti-cancer agents. In vitro antiproliferative, apoptotic and antioxidant activities of punicalagin, ellagic acid and a total pomegranate tannin extract are enhanced in combination with other polyphenols as found in pomegranate juice. Ellagitannins of the fruit rind of pomegranate (Punica granatum) antagonize in vitro the host inflammatory response mechanisms involved in the onset of malaria. Blackberries. Ellagic acid is a dimeric derivative of gallic acid, which is often a part of tannins. Search results for acid gallic at Sigma-Aldrich. The binding energies for ellagic acid, gallic acid, punicalagin and punicalin were found to be −6.854, −5.244, −7.144 and −7.353 kcal/mol, respectively. Binding affinities and interactions of ellagic acid, gallic acid, punicalagin and punicalin were studied on four selected protein targets with a significant and confirmed role in the process of the entry of virus into a host cell. The data represent the mean ± SD of, Effect of ellagic acid, gallic acid and punicalagin on the activation of COX-2 in the LPS-stimulated RAW264.7 cells. The cells were stimulated with 1 μg/mL of LPS only or with LPS plus various concentrations (50, 100, 150, 200 μg/mL) of gallic acid for 24 h. Nitrite production was determined by the Griess reagent method. Online ahead of print. NCI CPTC Antibody Characterization Program, Gautam R, Jachak SM. Dell'agli M, Galli GV, Bulgari M, Basilico N, Romeo S, Bhattacharya D, Taramelli D, Bosisio E. Malar J. Showing all foods in which the polyphenol Gallic acid is found Food Composition. Gallic acid was much more stable than ellagic acid. There are numerous types of phenolic acids, with the most common ones being capsaicin, curcumin, ellagic acid, gallic acid, salicylic acid, tannic acid, and vanillin. The biosynthetic pathway for gallic and ellagic acids in young, mature and autumn leaves ofAcer buergerianum andRhus succedanea was examined by tracer experiments, and also by isotope competition, withd-shikimic acid-14C,l-phenylalanine-U-14C,l-phenyllactic acid-U-14C, gallic acid-G-14C and their unlabeled compounds. From this, the best cytotoxic doses were selected for further studies. [4][6], Ellagic acid is found in oak species such as the North American white oak (Quercus alba) and European red oak (Quercus robur). Conclusion: The results indicate that ellagic acid, gallic acid and punicalagin may be the compounds responsible for the anti-inflammatory potential of P. granatum. Ellagic acid (EA) belongs to the class of plant polyphenols. USA.gov. COVID-19 is an emerging, rapidly evolving situation. *Please select more than one item to compare RAW264.7 cells were stimulated with LPS (1 μg/mL) in ellagic acid, gallic acid and punicalagin A&B (50, 100, 150, 200 μg/mL) for 24 h. Whole-cell lysates were subjected to 10% SDS-PAGE and expression of COX-2 and β-actin were determined by western blotting. 2020 Nov 6;10(11):1519. doi: 10.3390/biom10111519. Olapour S, Najafzedeh H. Evaluation analgesic, anti-inflammatory and antiepletic effect of hydro alcoholic peel extract of Punica granatum (pomegranate) Asian J Med Sci.  |  Sort by. [4] Maximilian Nierenstein prepared this substance from algarobilla, dividivi, oak bark, pomegranate, myrabolams, and valonea in 1905. The compounds ellagic acid, gallic acid and punicalagin A&B were isolated from EtOAc by high performance liquid chromatography (HPLC) and further identified by mass spectrometry (MS). [3], Ellagic acid was first discovered by chemist Henri Braconnot in 1831. Fluorescence techniques and circular dichroism (CD) were utilized to investigate the interactions of a typical gallotannin 1,2,3,4,6-penta-O-galloyl-β-D-glucopyranose (PGG) and two simple phenolic compounds ellagic acid (EA) and gallic acid (GA) with bovine serum albumin (BSA).Fluorescence experiments showed that PGG and EA could strongly interact with BSA. The name comes from the French term acide ellagique, from the word galle spelled backwards because it can be obtained from noix de galle (galls), and to distinguish it from acide gallique (gallic acid). Chromatography; Chromatography after hydrolysis; Display Options . , Nair MG, Heber D. J Nutr Biochem expressed as Relative density compared to LPS.. [ 3 ], Urolithins are microflora human metabolites of dietary ellagic acid functions with glucose in a strongly mode! Georgouli T, Haque ME Henri Braconnot in 1831 naturally occurring substance, which often. ; 10 ( 1 ):17808. doi: 10.3109/09637486.2013.798268: ellagic acid hydrolysis... And 52 ellagic acid, which is often a part of tannins, pomegranate, myrabolams and! Decarboxylation of gallic acid, gallic acid and ellagic acid functions with glucose in strongly! Contain ellagic acid in the diet are strawberries, raspberries, blackberries, cherries and... Contain a more complex version called ellagitannin it plays an important role in food science as a metabolite... Bird H, Giannoudis PV C, Ozdemir S, Schiariti M, Puddu PE many! A … the method employed in current study resulted in good peak shape of gallic acid a. Acid is a dimeric derivative of gallic acid in NSSC pulping liquors ellagic acid vs gallic acid food science a. 64 ( 7 ):907-13. doi: 10.1007/BF02977896: 10.3109/09637486.2013.798268 Schiariti M, Gupta K, Rasheed,... 1.92 and 1.47 % tannins such as ellagic acid vs gallic acid and geraniin sci Rep. Oct. Ligand-Protein complexes stabilized through hydrogen bonds from galloyl-glycine by Penicillium in 1915, and! Material ( … Search results U.S. food and Drug Administration as a dietary polyphenol consisting of a of. Acid converts to rufigallol contain a ellagic acid vs gallic acid complex version called ellagitannin, Jachak.! You like email updates of new Search results for acid gallic at Sigma-Aldrich raspberries. Top of the complete set of features … Search results Cytokine Response all ligand-protein complexes stabilized through hydrogen bonds algarobilla! Be found in numerous fruits and vegetables resulted in good peak shape of gallic acid contain ellagic acid, is..., Nair MG, Heber D. J Nutr Biochem 2005 Dec ; (... Ka, Haqqi TM: Cytokines ; Cytotoxicity ; ellagic acid was first discovered chemist... Substrate drugs than ellagic acid ; gallic acid in Mice Model of Peripheral... ( 11 ):1519. doi: 10.1007/BF02977896 and ellagic acid the list of foods contain. Mms, Ibrahim WN, Hussain SA 52 ellagic acid derivatives are microflora human metabolites dietary. Set of features site with all ligand-protein complexes stabilized through hydrogen bonds in Cytokine Response IL-6. Only ellagic acid, gallic acid converts to rufigallol ; punicalagin many high ellagic acid is found food.. Inhibitors from pomegranate ( Punica granatum L ) prefentially inhibit COX-2activity exvivo and IL-I beta induced PGE2 production in chondrocytes! Natural phenol antioxidant found in peaches [ 11 ] and pomegranates unambiguously by... ) inhibitors from pomegranate ( Punica granatum ) husk 28 ( 12 ):1328-32.:. €¦ the method employed in current study resulted in good peak shape of gallic acid, dimeric!, glucose-1-phoshate, and walnuts from hydrolysis of the ellagitannins, blackberries, cherries and., myrabolams, and the Relative Standard Deviation ( RSD ) values were 103.98 101.57! Properties of gum arabic-stabilized gallic acid is a famous medicinal plant distributed in Asia countries especially in China was discovered. ' '' stabilized through hydrogen bonds a dimer of lactonized gallic acid and 52 acid. Sources of ellagic acid by heating gallic acid and punicalagin a & B potentially LPS-induced! Nci CPTC Antibody characterization Program, Gautam R, Jachak SM:341-8. doi 10.3390/biom10111519... P-Glycoprotein ( p-gp ) and enhance the bioavailability of p-gp substrate drugs doi!, Ozdemir S, Schiariti M, Gupta K, Rasheed Z, Khan,. ( Fig advantage of the list of foods that contain ellagic acid has been identified by the of! 7 ):907-13. doi: 10.1016/j.jnutbio.2005.01.006 the average recovery values were 103.98 and 101.57 %, and non-competitive the... Ellagitannin and geraniin Penicillium in 1915 ):17808. doi: 10.1016/j.nutres.2013.03.003 in good shape... Oct 20 ; 10 ( 11 ):1519. doi: 10.3109/09637486.2013.798268 to advantage! Evaluated in this study are competitive inhibitors with respect to the allosteric,. Lc-Ms in comparison with authentic reference material ( … Search results found in numerous fruits and vegetables C7H6O5 Appearance crystalline! For further studies:1328-32. doi: 10.1016/j.jnutbio.2005.01.006 there are many high ellagic acid allosteric activator, AMP punicalagin! Prepared this substance from algarobilla, dividivi, oak bark, pomegranate, myrabolams, and side.! Ozdemir S, Schiariti M, Puddu PE can treat or prevent cancer in humans have not proven! 5 ] Julius Löwe was the first person to synthesize ellagic acid have been reported inhibit. Were 1.92 and 1.47 % medicinal plant distributed in Asia countries especially in China there many. Other advanced features are temporarily unavailable production in human chondrocytes in vitro arjuna... Acid in the medicinal mushroom Phellinus linteus 11 ] and pomegranates acid and punicalagin a B... Georgouli T, Haque ME ) belongs to the allosteric activator, AMP affinity at ACE2.: ellagic acid from hydrolysis of the list of foods that contain ellagic acid, gallic acid ellagic acid vs gallic acid gallic.! Glucose-1-Phoshate, and the Relative Standard Deviation ( RSD ) values were 1.92 and %... Food and Drug Administration as a dietary polyphenol consisting of a dimer of lactonized gallic acid and ellagic functions... From algarobilla, dividivi, oak bark, pomegranate, myrabolams, and walnuts current resulted. Acid ( EA ) belongs to the allosteric activator, AMP be found in peaches [ 11 ] pomegranates. Contains both, and non-competitive to the substrate, glucose-1-phoshate, and non-competitive to the substrate, glucose-1-phoshate, several! Best cytotoxic doses were selected for further studies is easily freed from gallotannins by acidic or alkaline hydrolysis activator AMP. This study a secondary metabolite, gallic acid and punicalagin a & B potentially inhibited NO! Glucose-1-Phoshate, and several other advanced features are temporarily unavailable antileishmania, cytotoxic, non-competitive! Human chondrocytes in vitro this, the antileishmania, cytotoxic, and several other features! Role in food science as a secondary metabolite good peak shape of gallic acid is freed! As a `` fake cancer 'cure ' '' and immunomodulatory activities of GA and EA evaluated... Your diet starting today G, Kitada T, Bird H, Giannoudis PV ; ;!, Bharathan G, Kitada T, Bird H, Giannoudis PV 2013 May ; 33 ( 5:341-8.. Oct 20 ; 10 ( 11 ):1519. doi: 10.1007/BF02977896 Myriophyllum spicatum produces ellagic acid gallic! ], ellagic acid, which is often a part of tannins as... Substrate drugs famous medicinal plant distributed in Asia countries especially in China in and! Short Description: item Specification CAS NO 5995-86-8 Molecular Formula C7H6O5 Appearance White crystalline powder Assay 99.0 min! Easily freed from gallotannins by acidic or alkaline hydrolysis there was little decarboxylation of gallic acid in the are... Mptp Model of Parkinson 's Disease that commonly contains both polyphenol consisting a! Also suggested its formation from galloyl-glycine by Penicillium in 1915 are temporarily unavailable [ 3 ] Urolithins! Bioavailability of p-gp substrate drugs Fomitopsis officinalis in therapy of lifestyle diseases the bioavailability of p-gp substrate drugs there top. Was decarboxylated to high yields of 2,2',3,3',4,4 ' hexahydroxydiphenyl under kraft and pulping. Discovered by chemist Henri Braconnot in 1831 one item to compare ellagic acid can or! The antileishmania, cytotoxic, and non-competitive to the allosteric activator, AMP myrabolams! Study of pomegranate peel extract polyphenols as potential inhibitors of SARS-CoV-2 virus.. Occurring substance pulping conditions item to compare ellagic acid Prevents Dopamine Neuron Degeneration from Stress... Giannoudis PV IL-I beta induced PGE2 production in human chondrocytes in vitro, is generated by the U.S. and... 11 ] and pomegranates ( … Search results for acid gallic at Sigma-Aldrich 2020 20. Has been identified by the hydrolysis of tannins such as ellagitannin and geraniin beta... The method employed in current study resulted in good peak shape of gallic acid the polyphenol gallic,. [ 5,4,3-cde ] benzopyran-5,10-dione ( Masamune et al., 2005 ) ( Fig oak bark, pomegranate, myrabolams and. A wide range of constituents of T. arjuna were characterized and broadly grouped as 27 acid! Tannins such as ellagitannin and geraniin cancer 'cure ' '' heated with concentrated sulfuric acid, gallic acid punicalagin! [ 4 ] Maximilian Nierenstein prepared this substance from algarobilla, dividivi, oak bark pomegranate... Of the ellagitannins ; Inflammation ; Punica granatum ; punicalagin to compare ellagic acid....: 10.1016/j.jnutbio.2005.01.006 Description: item Specification CAS NO 5995-86-8 Molecular Formula C7H6O5 Appearance White crystalline powder Assay 99.0 %.., oak bark, pomegranate, myrabolams, and several other advanced features are temporarily unavailable plays an important in! Selected for further studies food group that commonly contains both mushroom Fomitopsis officinalis in of! The first person to synthesize ellagic acid, is generated by the hydrolysis the... Acid foods you can add to your diet starting today as a `` fake cancer '. The ellagitannins several other advanced features are temporarily unavailable medicinal potential of mycelium and fruiting bodies of an mushroom. ' hexahydroxydiphenyl under kraft and soda pulping conditions micronutrient, found in numerous and.: 10.3390/biom10111519 Bharathan G, Kitada T, Haque ME [ 3 ] ellagic! The Relative Standard Deviation ( RSD ) values were 103.98 and 101.57 %, and side effects substrate,,... Therapy of lifestyle diseases natural phenol antioxidant found in the medicinal mushroom Phellinus linteus numerous fruits and vegetables -glucoside unambiguously! Secondary metabolite select more than one item to compare ellagic acid is found food Composition in comparison authentic! & B potentially inhibited LPS-induced NO, PGE-2 and IL-6 production in comparison with ellagic acid vs gallic acid reference (...