the electronic edition of the Official Journal of the European Union should be consulted. Identification number: UN 3082 Packing group: III DOT Hazardous Substance(s): Methylene diphenyl diisocyanate, Methylene diphenyl diisocyanate . The type of uses and classifications may vary between different submissions to ECHA and for a full understanding it is recommended to consult the source data. These notifications can be provided by manufacturers, importers and downstream users. 7 and points 2 and 3 of the Annex to Directive 94/33/EC, to which young persons (under 18 years of age) may not be exposed at the workplace. It is not soluble in water. endstream endobj startxref MDA is consumed mainly as a precursor to 4,4 ́-methylene diphenyl diisocyanate (MDI). 80 0 obj <> endobj 10.3 Possibility of hazardous reactions. This substance has been found in the following regulatory activities (directly, or inheriting the regulatory context of a parent substance): This list represents a calculated inventory of substances based on the list of harmonized substances contained in Table 3 of Annex VI to the CLP Regulation (1272/2008/EC). Substances according to Hazardous Waste Properties: Annex III, Directive 2008/98/EC, 22 November 2008, amended by Directive 2018/851/EU, 14 June 2018, Registration, Evaluation, Authorisation and Restriction of Chemicals, Chemical Agents Directive and Carcinogens or Mutagens Directive, Plastic Materials and Articles Regulation, Protection of Pregnant and Breastfeeding Workers Directive, Safety and/or Health Signs at Work Directive, EC Inventory, Pre-Registration process, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, Pre-Registration process, Cosmetic Products Regulation, Annex II - Prohibited Substances, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, C&L Inventory, Pre-Registration process, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, 4,4'-methylenediphenyl diisocyanate; diphenylmethane-4,4'-diisocyanate, CAD - Chemical Agents Directive, Art. REACH Annex XVII. In order to process your orders without delay, we request that you provide the required business documentation to purchase this product. Stability and reactivity 10.1 Reactivity. The molecular structure is based on structures generated from information available in ECHA’s databases. Substances for which classification and labelling data have been notified to ECHA by manufacturers or importers. The source of the information is mentioned in the introductory sentence of the hazard statements. The EU Ecolabel may not be awarded to substances or mixtures classified as such. Guidance To help minimize the formation of a dimer, an insoluble white solid that may impact the quality of the product, 4,4’-methylene diphenyl diisocyanate (MDI) is usually stored and transported in drums at temperatures below 41°F (5°C). First-aid measures 66/2010/EC, L 27/1, 30 Jan 2010 (T. 3 of Anx VI to CLP; Candidate List of SVHCs), EU. endstream endobj 81 0 obj <> endobj 82 0 obj <> endobj 83 0 obj <>stream Impurities or additives: When a specific critical property is calculated from industry data and where the majority of data submitters have indicated that the property relates to cases containing impurities and/or additives, then the respective critical property icon is modified with an asterisk (*). inside a watch) or with very low concentrations considered not to pose risks to human health or the environment. 2(b)(i) - Hazardous Agents, Cosmetic Products Regulation, Annex II - Prohibited Substances, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, FCM and Articles Regulation, Annex I - Authorised Substances, Protection of Pregnant and Breastfeeding Workers Directive, Annex I+II, Workplace Signs - minimum requirements & signs on containers and pipes, Waste Framework Directive, Annex III - Waste - Hazardous Properties, Fertiliser Regulation- Annex I, E.3 (chelating and complexing agents), Substances of very high concern identification, Recommendation for the Authorisation List, Getting started with EU chemicals legislation, Classification of substances and mixtures, Harmonised classification and labelling (CLH). The EC Number is the numerical identifier for substances in the EC Inventory. 92/85/EEC on Pregnant Workers, 28 November 1992 (updated by table 3 of Annex VI to CLP, 5 Oct 2018), EU. h�bbd``b`� �@�q+�`��q��9� H��- � �=�P� b9 ��)�@�4�Ҍ�����$)'�3.�` ��G The Prior Informed Consent Regulation administers the import and export of certain hazardous chemicals and places obligations on companies who wish to export these chemicals to non-EU countries. More information about Classification and Labelling is available in the Regulations section of ECHA website. If the substance was not covered by the EC Inventory, ECHA attributes a list number in the same format, starting with the numbers 6, 7, 8 or 9. MDI and other isocyanates may also cause hypersensitivity pneumonitis, another allergic lung ... Methylene diphenyl diisocyanate (MDI) 0.051 (0.005 ppm) 0.2 (0.02 ppm) 0.005 ppm . The ‘Hazard classification and labelling’ section shows the hazards of a substance based on the standardised system of statements and pictograms established under the CLP (Classification Labelling and Packaging) Regulation. Occupational exposure limit (OEL) values are derived within two legal frameworks that form an integral part of the EU’s mechanism for protecting the health of workers. Hazard statements were adapted to improve readability and may not correspond textually to the hazard statements codes description in the European Union Specific Hazard Statements (EUH) or the. • MDI and TDI Nomenclature, Gilbert International Limited 2001, GIL Report Number 2001/B, B. Tury, D.S. This substance is used for the manufacture of: chemicals. REACH registration dossiers have greater data requirements (such as supporting studies) than do notifications under CLP. no data available. National Center for Environmental Assessment, Office of Research and Development, … This information is only displayed if the substance is well–defined, its identity is not claimed confidential and there is sufficient information available in ECHA’s databases for ECHA’s algorithms to generate a molecular structure. In these cases, Infocards may not identify all substances in the group.Therefore it does not represent official and legally–binding information. The per substance REACH registration status is being calculated and will be made available as soon as possible. The “UN Sub-committee of Experts on Transport of Dangerous Goods” decided in July 1994 to remove Diphenylmethane Diisocyanate (MDI) from the list of hazardous goods. 6.U.S. 101-68-8 and 9016-87-9) in Support of Summary Information on the Integrated Risk Information System (IRIS). %PDF-1.5 %���� The annexes to this directive provide detailed information about the minimum requirements for all safety and health signs. This substance is used in the following areas: building & construction work, health services and printing and recorded media reproduction. This list contains biological and chemical agents, in accordance with Art. Substances may have impurities and additives that lead to different classifications. The CAS number is the substance numerical identifier assigned by the Chemical Abstracts Service, a division of the American Chemical Society, to substances registered in the CAS registry database. This section provides an overview of the calculated volume at which the substance is manufactured or imported to the European Economic Area (EU28 + Iceland, Liechtenstein and Norway). This substance is used for the manufacture of: machinery and vehicles. The described Product category (i.e. This directive requires employers to ensure proper signage is posted in areas where hazards cannot be avoided or reduced. CHEMTREC operators are available 24 hours a day, seven days a week. InfoCards are generated automatically based on the data available at the time of generation. Other relevant information includes the following: To see the full list of notified classifications and to get more information on impurities and additives relevant to classification please consult the C&L Inventory. While the harmonized list covers many hazardous substances, other ones not listed may also meet the classification criteria in accordance with the CLP. Close Find out more on how we use cookies. The ‘Properties of concern’ section shows ECHA-assigned graphical indicators for certain substance properties that are regarded as being of relevance or importance to human health and/or the environment based on the information provided to the Agency. Harmonisation is based on the substance’s physical, toxicological and eco-toxicological hazard assessment. UN/NA datasheets display several items from the Hazmat Table: proper shipping names, hazard classes and divisions (explosives may also include a compatibility group letter label codes, and special notes relating to shipping location, shipping name, and whether the material is an inhalation hazard. Danger! Substances for which certain uses are Restricted under REACH at EU level. … General Description Diphenylmethane-4,4-diisocyanate is a light yellow colored solid. BPR regulation aims to improve the functioning of the biocidal products market in the EU, while ensuring a high level of protection for humans and the environment. Toluene Diisocyanate (TDI) is classified and regulated as hazardous for handling and transport. The molecular formula identifies each type of element by its chemical symbol and identifies the number of atoms of each element found in one discrete molecule of the substance. This information is only displayed if the substance is well-defined, its identity is not claimed confidential and there is sufficient information available in ECHA’s databases for ECHA’s algorithms to generate a molecular structure. "�E��z���!9�%��E$�0?�DJrC� A flammable liquid.Isocyanates and thioisocyanates, such as DIPHENYLMETHANE-4,4'-DIISOCYANATE, are incompatible with many classes … The ‘Substance identity’ section is calculated from substance identification information from all ECHA databases. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use. Section 1 - Identification of the substance/mixture and of the company/undertaking This is unique source of information on the chemicals manufactured and imported in Europe. ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment. C&L Inventory . If no EU harmonised classification and labelling exists and the substance was not registered under REACH, information derived from classification and labelling (C&L) notifications to ECHA under CLP Regulation is displayed under this section. This website uses cookies to ensure you get the best experience on our websites. This list is generated from hazardous substances listed in Directive 92/85/EEC and from table 3.2 of Annex VI of the CLP. If generated, an InChI string will also be generated and made available for searching. Substances may be grouped together under a specific regulatory activity for more efficient risk management and legislative processing (e.g. Guidance on safe use - recommendations by substance registrant on the proper use of the substance in various situations. 11. The purpose of the information provided under this section is to highlight the substance hazardousness in a readable format. It is the responsibility of the substance manufacturers and importers to consult official publications, e.g. Substances which have been registered and can be placed on the EEA market by those companies with a valid registration. IDH number: 1506861 Product name: LOCTITE HB E202 known as PURBOND HB E202 Page 6 of 6 International Air Transportation (ICAO/IATA) Additionally, if available, information on the use of the substance and how consumers and workers are likely to be exposed to it can also be displayed here. fused 4,4’-Methylene Diphenyl Diisocyanate (MDI). This section provides links to the list of precautions (precautionary statements) and to the guidance on safe use, if they have been provided in REACH registration dossiers. restriction on "Lead and its compounds"). DOT Environmentally Hazardous Substance, N.O.S. Methylenediphenyl 4,4 -Diisocyanate 97.0 %, TCI America 25G Chemicals:Organic Compounds:Benzenoids:Benzene and substituted derivatives:Diphenylmethanes The use information is displayed per substance life cycle stage (consumer use, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites or in manufacturing). … Resources for Diisocyanates Emergency Response Please note: Precautionary measures and guidance on safe use concern the use and handling of the specific substance as such, not of the presence of the substance in other articles or mixtures. The Support section provides tools and practical guidance to companies which have responsibilities under the EU chemicals legislation. Product Number: D0897: Purity / Analysis Method >97.0%(T) Molecular Formula / Molecular Weight: C__1__5H__1__0N__2O__2 = 250.26 : Physical State (20 deg.C) Solid: Storage Temperature: 0-10°C: Store Under Inert Gas: Store under inert gas: Condition to Avoid: Moisture Sensitive,Heat Sensitive: CAS RN: 101-68-8: Reaxys Registry Number… Also referred to as the Plastics Implementation Measure (PIM), this Regulation provides the Union List of monomers and other substances authorized in the manufacture of food contact plastics. 4,4' Methylene Diphenyl Diisocyanate Reportable Quantity: 5000 lbs When in individual containers of less than the substance RQ, this material ships as non-regulated. %%EOF disodium tetraborate EC no. Tool showing an overview of substances in various key regulatory processes that authorities are working on. Prohibited Substances: Annex II, Regulation 1223/2009/EC on Cosmetic Products, as amended by Regulation 2019/1966/EU, 28 November 2019, EU. 590 Revision Date: 1/8/2019 Version: 10.0 GHS Compliant . MDI is a precursor to many polyurethane foams. 4,4'-Diphenylmethane diisocyanate, MDI, Methylene di-p-phenylene ester of isocyanic acid, Methylene bis(4-phenyl isocyanate) White to light-yellow, odorless flakes. (3) MDI is the usual abbreviation for monomeric methylene diphenyl diisocyanate, (CAS# 101-68-8). A prioritisation hierarchy means that data is taken from harmonised C&L data and regulatory lists first, then REACH registrations and finally from CLP notifications. Table 3 of Annex VI to CLP Regulation); and (2) the Candidate List of substances of very high concern (SVHC). The content of monomeric MDI generally is between 45% and 65% on a w/w basis (Mobay, 1983). Methylene diphenyl diisocyanate (MDI) in commercial form typically exists as a mixture of 4,4'-MDI (monomer) and certain oligomers of MDI (Encyclopedia of Chemical Technology, 1983). CAS number: 101–68–8 NIOSH REL: 0.05 mg/m 3 (0.005 ppm) TWA, 0.2 mg/m 3 (0.020 ppm) 10-minute CEILING. The CLP Regulation makes sure that the hazards presented by chemicals are clearly communicated to workers and consumers in the European Union. Note that for readability purposes, only the pictograms, signal words and hazard statements referred in more than 5% of the notifications under CLP are displayed. 0.02 . Containers above RQ ship as: Agency Proper Shipping Name UN Number Packing Group Hazard Class . It may be toxic by … h�b```f``�d`e`�p``@ �(GCT䎒��N]���eX2�v2�aig�e`H�����l R�,����`�Wa��fH�l�۶��ʚå���PB+!� cEsE�[EGG�y{sxGP���+�*p���Ӟ ia � ��2�3,�[�3A_!��&i�Lf�����x��xO�%0�Hi: ���y@����X����"�Ϩ ` �3?# Release to the environment of this substance can occur from industrial use: manufacturing of the substance, formulation of mixtures and for thermoplastic manufacture. The precautionary measures and guidance on safe use are as submitted to ECHA by registrants under the REACH Regulation. This database contains substances that have been assigned hazard property (HP) waste codes 1-15, as defined in terms of the hazard class & category, hazard (H) statement, and/or concentration limits provided in Annex III of the Waste Framework Directive (2008/98/EC). [Note: A liquid above 99°F.] The ‘Hazard classification’ and labelling section uses the signal word, pictogram(s) and hazard statements of the substance under the harmonised classification and labelling (CLH) as its primary source of information. Brain injury, 8(3):285–294. 4,4-Methylene Diphenyl Diisocyanate (MDI), All Isomers CAS Registry Number 101-68-8 1,6-Hexamethylene Diisocyanate (HDI), All Isomers CAS Registry Number 822-06-0 Prepared by Toxicology, Risk Assessment, and Research Division Development Support Document Proposed, March 6, 2019 To 4,4 ́-methylene diphenyl diisocyanate: a report of five cases the per substance REACH dossiers! To CLP ; Candidate list of SVHCs ), EU ( MDI ) ( CAS # 101-68-8 ) substance various! Substance hazardousness in a readable format the UN Global Harmonised System ( GHS ) and European.... Than 5 % of total occurrences are displayed, e.g also automatically generated and made as... 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